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MEP was statistically able to predict ICU-AW but area under (AUC) receiving operating curves showed weak predictive ability (AUC: 0.66 (95% IC 0.55вЂ“0.77 pвЂ‰<вЂ‰0.01) for a threshold valueвЂ‰в‰¤вЂ‰49 cmH 2O. No other outcomes were different between groups. Patients with low MEP presented more ICU-AW compared to normal MEP patients (64% vs. Inversely, higher body mass index was associated with higher MEP. Patients with low MEP received more catecholamines (pвЂ‰=вЂ‰0.04) and a higher duration of mechanical ventilation (pвЂ‰=вЂ‰0.001). Results: Due to the paucity of data reporting threshold value for expiratory muscle weakness, we considered our median value (47 cmH 2O (IQR 44)) as the threshold value for expiratory muscle weakness group (MEPвЂ‰в‰¤вЂ‰47 cmH 2O) and normal expiratory muscle group (MEPвЂ‰>вЂ‰47В cmH 2O). MEP diagnostic accuracy to predict ICU-AW (ICU acquired weakness), weaning success and sursvival within 30В days were assessed using expiratory muscle strength as absolute values (cmH 2O), as %predicted values and as %lower limit of normal.

#X PLANE CIRRUS JET MANUAL TROLLEY TRIAL#

Maximal expiratory pressure (MEP) measurement was carried out during spontaneous breathing trial using a manometer with an unidirectional valve.

Patients and methods: This study is a secondary analysis of our previously described cohort of 124 patients ventilated for at least 24В h assessed for respiratory muscles function. However, few studies reported potential factors leading to expiratory muscle weakness and its importance on weaning success or survival after mechanical ventilation. Several authors stated these muscles importance in cough capacity, contractile efficiency of the diaphragm or reduction of hyperinflation. Rationale: Expiratory muscles has recently been stated as the В«neglected componentВ» in mechanically ventilated patient. COK-1 Expiratory muscle weakness quantified by maximal expiratory pressure may be insufficient in predicting critical outcomes in mechanically ventilated patients Yann Combret 1, Guillaume Prieur 1, Francis-Edouard Gravier 2, Tristan Bonnevie 2, Olivier Contal 3, Bouchra Lamia 1, Clement Medrinal 1 1Groupe Hospitalier du Havre, Le Havre, France 2ADIR Association, Rouen, Fs 3Haute Ecole de SantГ© Vaud, Lausanne, Switzerland Correspondence: Yann Combret Intensive Care 2020, 10 (Suppl 1):COK-1

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